Figure 4.
Metabolomics analysis of MOTS-c VS TBI groups (n=7).
Notes: (A) Score scatter plot of the OPLS-DA model. (B) Volcano plot. The red and blue points represent the up-regulated and down-regulated metabolites, respectively. The bubble size represents the VIP value. (C) Heatmap of hierarchical clustering analysis for the MOTS-c and TBI groups. Red and blue represent up-regulation and down-regulation, respectively (DEMs: VIP>1.0 and p<0.05).
Abbreviations: MOTS-c, mitochondrial open reading frame of the 12S rRNA-c; TBI, traumatic brain injury.