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. Author manuscript; available in PMC: 2024 Jul 24.
Published in final edited form as: Stat Med. 2018 Jul 12;37(27):4071–4082. doi: 10.1002/sim.7899

TABLE 1.

Estimates of size and power for three log rank tests under simulation design 1 with M=30 clusters and heavy (50%) censoring. Positive/Negative cluster size informativeness indicates that larger/smaller clusters tended to have longer survival times. Group size informativeness indicates which group tended to be over-represented in clusters with longer survival times. LR = log rank, SLR = stratified log rank, CWLR = cluster size-weighted log rank, GWLR = group size-weighted log rank, and Frailty = frailty model

Informativeness Power
Group Size Cluster Size Test Size β=0.2 β=0.4 β=0.6 β=0.8
None None LR 0.054 0.10 0.22 0.44 0.67
SLR 0.048 0.16 0.49 0.83 0.97
CWLR 0.061 0.11 0.22 0.42 0.64
GWLR 0.055 0.14 0.37 0.68 0.89
Frailty 0.045 0.17 0.50 0.84 0.98
Positive LR 0.044 0.09 0.23 0.45 0.67
SLR 0.051 0.17 0.50 0.85 0.97
CWLR 0.057 0.08 0.17 0.30 0.47
GWLR 0.055 0.11 0.24 0.47 0.70
Frailty 0.042 0.17 0.51 0.86 0.98
Negative LR 0.043 0.11 0.33 0.62 0.84
SLR 0.050 0.16 0.48 0.81 0.96
CWLR 0.055 0.10 0.26 0.48 0.69
GWLR 0.055 0.16 0.47 0.78 0.95
Frailty 0.057 0.16 0.50 0.84 0.97
Group 0 None LR 1.000 1.00 1.00 1.00 1.00
SLR 0.058 0.13 0.36 0.70 0.90
CWLR 1.000 1.00 1.00 1.00 1.00
GWLR 0.055 0.10 0.26 0.53 0.79
Frailty 0.095 0.29 0.61 0.89 0.97
Positive LR 1.000 1.00 1.00 1.00 1.00
SLR 0.052 0.11 0.35 0.63 0.85
CWLR 0.994 1.00 1.00 1.00 1.00
GWLR 0.057 0.08 0.20 0.37 0.60
Frailty 0.074 0.23 0.53 0.79 0.95
Negative LR 1.000 1.00 1.00 1.00 1.00
SLR 0.045 0.14 0.41 0.75 0.93
CWLR 1.000 1.00 1.00 1.00 1.00
GWLR 0.053 0.11 0.33 0.59 0.85
Frailty 0.097 0.32 0.68 0.91 0.98
Group 1 None LR 1.000 1.00 1.00 0.99 0.97
SLR 0.051 0.13 0.37 0.70 0.91
CWLR 1.000 1.00 0.98 0.94 0.83
GWLR 0.058 0.14 0.33 0.59 0.81
Frailty 0.090 0.07 0.22 0.54 0.81
Positive LR 1.000 1.00 0.98 0.95 0.86
SLR 0.053 0.15 0.38 0.67 0.89
CWLR 1.000 0.98 0.94 0.87 0.72
GWLR 0.052 0.12 0.25 0.46 0.63
Frailty 0.075 0.08 0.25 0.52 0.78
Negative LR 1.000 1.00 0.97 0.86 0.64
SLR 0.048 0.14 0.43 0.73 0.94
CWLR 1.000 1.00 0.98 0.89 0.72
GWLR 0.066 0.16 0.40 0.67 0.88
Frailty 0.093 0.07 0.25 0.57 0.85