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. 2022 Nov 9;23(11):380. doi: 10.31083/j.rcm2311380

Table 4.

Comparison of statins and PCSK9 inhibitors in the relationship with the kidney.

Relationship with the kidney Statins PCSK9 inhibitors
Renal elimination YES NO
Proteinuria Induce proteinuria Do not induce proteinuria
eGFR Cause decreases in eGFR Have no effect on eGFR
AKI YES YES

eGFR, estimated glomerular filtration rate; AKI, acute kidney injury; PCSK9, proprotein convertase subtilisin/kexin type 9.