Table 4.
Comparison of statins and PCSK9 inhibitors in the relationship with the kidney.
Relationship with the kidney | Statins | PCSK9 inhibitors |
Renal elimination | YES | NO |
Proteinuria | Induce proteinuria | Do not induce proteinuria |
eGFR | Cause decreases in eGFR | Have no effect on eGFR |
AKI | YES | YES |
eGFR, estimated glomerular filtration rate; AKI, acute kidney injury; PCSK9, proprotein convertase subtilisin/kexin type 9.