Table 2.
Univariate analysis for bone metabolism markers.
| Characteristics | Statisticsa | β-CTX β(95%CI) p-value |
P1NP β(95%CI) p-value |
|---|---|---|---|
| Age, years | 69.04 ± 11.02 | 0.00 (−0.00, 0.00) 0.35 |
−0.02 (−0.22, 0.19) 0.88 |
| BMI, kg/m2 | 22.96 ± 3.35 | 0.00 (−0.01, 0.01) 0.73 |
0.09 (−0.57, 0.76) 0.79 |
| TC, mmol/L | 4.35 ± 0.89 | −0.03 (−0.05, −0.00) 0.04 |
−2.61 (−5.57, 0.35) 0.09 |
| HDL, mmol/L | 1.33 ± 0.29 | −0.12 (−0.20, −0.04) 0.004 |
−8.57 (−17.61, 0.46) 0.06 |
| Calcium, mmol/L | 2.22 ± 0.12 | 0.18 (0.01, 0.34) 0.04 |
15.96 (−2.11, 34.03) 0.08 |
| Platelet count, ×109/L | 177.12 ± 61.18 | 0.00 (0.00, 0.00) 0.003 |
0.05 (0.01, 0.08) 0.01 |
| SIRI | 2.40 ± 2.18 | −0.03 (−0.04, −0.02) <0.001 |
−2.70 (−3.70, −1.70) <0.001 |
| Sex, N (%) | |||
| female | 486 (66.39%) | Reference | Reference |
| male | 246 (33.61%) | −0.01 (−0.05, 0.04) 0.72 |
1.13 (−3.59, 5.84) 0.64 |
| Smoke, N (%) | |||
| No | 684 (93.44%) | Reference | Reference |
| Yes | 48 (6.56%) | −0.07 (−0.15, 0.01) 0.11 |
−4.43 (−13.42, 4.56) 0.33 |
| Drink, N (%) | |||
| No | 704 (96.17%) | Reference | Reference |
| Yes | 28 (3.83%) | −0.04 (−0.14, 0.07) 0.51 |
−3.95 (−15.55, 7.66) 0.51 |
| Hypertension, N (%) | |||
| no | 642 (87.70%) | Reference | Reference |
| yes | 90 (12.30%) | 0.05 (−0.01, 0.11) 0.12 |
5.00 (−1.77, 11.77) 0.15 |
| Diabetes, N (%) | |||
| No | 702 (95.90%) | Reference | Reference |
| Yes | 30 (4.10%) | 0.01 (−0.09, 0.11) 0.86 |
3.62 (−7.61, 14.86) 0.53 |
| Age, years, N (%) | |||
| >50, ≤70 | 420 (57.38%) | Reference | Reference |
| >70 | 312 (42.62%) | 0.01 (−0.03, 0.05) 0.67 |
−1.68 (−6.18, 2.82) 0.46 |
| CCI, N (%) | |||
| 0 | 655 (89.48%) | Reference | Reference |
| 1 | 58 (7.92%) | −0.01 (−0.08, 0.07) 0.82 |
2.76 (−5.50, 11.02) 0.51 |
| ≥2 | 19 (2.60%) | −0.01 (−0.14, 0.11) 0.83 |
−0.36 (−14.38, 13.67) 0.96 |
| BMI, kg/m2, N (%) | |||
| ≤18.5 | 73 (9.97%) | Reference | Reference |
| >18.5, ≤23.9 | 362 (49.45%) | 0.03 (−0.04, 0.10) 0.34 |
6.33 (−1.39, 14.04) 0.11 |
| >23.9, ≤28.0 | 255 (34.84%) | −0.01 (−0.08, 0.06) 0.83 |
1.43 (−6.55, 9.41) 0.73 |
| >28.0 | 42 (5.74%) | 0.06 (−0.05, 0.16) 0.30 |
5.05 (−6.60, 16.69) 0.40 |
aFor continuous variables.bThe dependent variable was bone turnover markers and β is the result of univariate analysis for bone turnover markers.BMI, body mass index; TC, total cholesterol; HDL, high-density lipoprotein; β-CTX, beta-C-terminal telopeptide of type I collagen; P1NP, procollagen type I N-terminal propeptide; SIRI, systemic inflammatory response index; CCI, Charlson comorbidity index.