TABLE 1.

Anti-cancer cellular pathways involved in S. marianum.

Cancers	Cells	Pathways	Ref
Hepatocellular carcinoma	HCC	HGF/c-Met、Wnt/β-catenin	Yassin et al. (2022)
Gastric cancer	SGC-7901	P53/p21、Caspase、PI3K/Akt/mTOR	Mi et al. (2022)
Gastric cancer	BGC-823	CDK1、Caspase	Fallah et al. (2021)
Gastric cancer	HGC-27	CDK1、Cyclin B1、Caspase	Mi et al. (2022)
Lung cancer	NSCLC	NFκB、JAK/STAT	Verdura et al. (2021)
Kidney cancer	SN12K1	P53/p21、TGFβ、PI3K/Akt/mTOR	Yassin et al. (2021)
Bladder cancer	TCC-SUP	Cip1/p21、Kip1/p27、CDK	Gándara et al. (2014)
Bladder cancer	T-24	Cip1/p21、Kip1/p27、CDK	Gándara et al. (2014)
Cervical cancer	HeLa	PI3K/Akt/mTOR、Caspase	You et al. (2020)
Prostate cancer	LNCaP	Cip1/p21、Kip1/p27	Wu et al. (2023b)
Breast cancer	MCF-7	ER	Zheng et al. (2016)
Breast cancer	SK-BR-3	HER-2	Zheng et al. (2016)
Colon cancer	HT-29	Cip1/p21、Kip1/p27	Fallah et al. (2021)
Skin cancer	HaCaT	Kip1/p27、Cip1/p21、ERK、JNK	Yassin et al. (2022)