Table 2.

Prognostic impact of Cancer Patient Pathway implementation

Characteristics	Total	Median OS	Unadjusted analyses		Adjusted analyses
	N (%)	Months	Hazard ratio (95% CI)	P-value	Hazard ratio (95% CI)	P-value
CPP
Pre-CPP	729 (65)	12.3	1		1
Post-CPP	396 (35)	13.7	0.88 (0.77–0.99)	0.039	0.73 (0.64–0.83)	< 0.001
Sex
Male	668 (59)	12.8	1	-	1	-
Female	457 (41)	13.2	0.86 (0.76–0.97)	0.014	0.87 (0.77–0.98)	0.023
Age (years)
<60	482 (43)	15.6	1	-	1	-
60–69	387 (34)	12.6	1.54 (1.34–1.77)	< 0.001	1.52 (1.32–1.74)	< 0.001
≥70	256 (23)	9.1	2.31 (1.97–2.70)	< 0.001	1.51 (1.22–1.85)	< 0.001
Tumor location
Right side	562 (50)	13.0	1	-	1	-
Left side	528 (47)	12.9	0.97 (0.86–1.10)	0.579	1.04 (0.92–1.17)	0.574
Midline	12 (1.1)	13.7	0.97 (0.55–1.71)	0.911	0.93 (0.52–1.66)	0.814
Bilateral	23 (2.0)	9.1	1.67 (1.10–2.54)	0.016	1.24 (0.80–1.92)	0.327
Tumor focality
Solitary	1025 (91)	13.3	1	-	1	-
Multifocal	100 (8.9)	9.2	1.41 (1.14–1.74)	0.001	1.27 (1.02–1.58)	0.031
Surgical resection
GTR	329 (29)	16.4	1	-	1	-
STR	682 (61)	12.1	1.63 (1.42–1.87)	< 0.001	1.58 (1.38–1.82)	< 0.001
Biopsy	114 (10)	8.3	2.39 (1.92–2.96)	< 0.001	1.85 (1.46–2.33)	< 0.001
Radiotherapy
54–60 Gy	889 (79)	14.8	1		1
30–40.05 Gy	236 (21)	7.3	2.72 (2.34–3.15)	< 0.001	2.43 (1.97–2.99)	< 0.001

Significant p-values highlighted in bold

AbbreviationsOS overall survival; CI confidence interval; GTR gross total resection; STR subtotal resection; Gy gray