Table 2.
Characteristics of patients with hypertensive disorders of pregnancy by discharge antihypertensive medication
| Overall (n=57,254) | None (n=49,295) | Labetalol only (n=4,288) | Nifedipine only (n=2,426) | Two or more (n=1,245) | |
|---|---|---|---|---|---|
| Hypertensive diagnosis | |||||
| Gestational hypertension | 28410 (49.6) | 27941 (56.7) | 255 (5.9) | 192 (7.9) | 22 (1.8) |
| Pre-existing hypertension | 7582 (13.2) | 5836 (11.8) | 1205 (28.1) | 381 (15.7) | 160 (12.9) |
| Non-severe pre-eclampsia | 9155 (16.0) | 8351 (16.9) | 419 (9.8) | 323 (13.3) | 62 (5.0) |
| Pre-existing hypertension with preeclampsia | 1359 (2.4) | 786 (1.6) | 302 (7.0) | 155 (6.4) | 116 (9.3) |
| Severe pre-eclampsia | 10748 (18.8) | 6381 (12.9) | 2107 (49.1) | 1375 (56.7) | 885 (71.1) |
| Last systolic blood pressure, mm Hg, n (%) | |||||
| ≤120 | 16610 (29.0) | 16059 (32.6) | 300 (7.0) | 170 (7.0) | 81 (6.5) |
| 121–130 | 17383 (30.4) | 16019 (32.5) | 687 (16.0) | 475 (19.6) | 202 (16.2) |
| 131–140 | 15221 (26.6) | 12513 (25.4) | 1426 (33.3) | 882 (36.4) | 400 (32.1) |
| 141–150 | 6529 (11.4) | 4110 (8.3) | 1333 (31.1) | 711 (29.3) | 375 (30.1) |
| >150 | 1511 (2.6) | 594 (1.2) | 542 (12.6) | 188 (7.7) | 187 (15.0) |
| Last diastolic blood pressure >80 mm Hg, n (%) | 20021 (35.0) | 15034 (30.5) | 2594 (60.5) | 1594 (65.7) | 799 (64.2) |
| Patient age, years, n (%) | |||||
| < 25 | 9522 (16.6) | 8640 (17.5) | 464 (10.8) | 298 (12.3) | 120 (9.6) |
| 25 – 29 | 14933 (26.1) | 13322 (27.0) | 865 (20.2) | 518 (21.4) | 228 (18.3) |
| 30 – 34 | 18996 (33.2) | 16307 (33.1) | 1440 (33.6) | 832 (34.3) | 417 (33.5) |
| ≥ 35 | 13803 (24.1) | 11026 (22.4) | 1519 (35.4) | 778 (32.1) | 480 (38.6) |
| Pre-pregnancy BMI, kg/m2, n (%) | |||||
| < 25.0 | 16860 (29.4) | 15000 (30.4) | 948 (22.1) | 659 (27.2) | 253 (20.3) |
| 25.0 – 29.9 | 15100 (26.4) | 13097 (26.6) | 1072 (25.0) | 616 (25.4) | 315 (25.3) |
| ≥ 30.0 | 22476 (39.3) | 18769 (38.1) | 2047 (47.7) | 1035 (42.7) | 625 (50.2) |
| Missing | 2818 (4.9) | 2429 (4.9) | 221 (5.2) | 116 (4.8) | 52 (4.2) |
| Patient race/ethnicity, n (%) | |||||
| Asian/Pacific Islander | 10824 (18.9) | 8949 (18.2) | 1032 (24.1) | 554 (22.8) | 289 (23.2) |
| Black | 5096 (8.9) | 4026 (8.2) | 524 (12.2) | 295 (12.2) | 251 (20.2) |
| Hispanic | 14361 (25.1) | 12454 (25.3) | 1029 (24.0) | 592 (24.4) | 286 (23.0) |
| Multiracial | 1772 (3.1) | 1510 (3.1) | 134 (3.1) | 90 (3.7) | 38 (3.1) |
| White | 23682 (41.4) | 21092 (42.8) | 1428 (33.3) | 825 (34.0) | 337 (27.1) |
| Other | 835 (1.5) | 678 (1.4) | 91 (2.1) | 42 (1.7) | 24 (1.9) |
| Unknown or missing | 684 (1.2) | 586 (1.2) | 50 (1.2) | 28 (1.2) | 20 (1.6) |
| Parity | |||||
| Nulliparous | 29333 (51.2) | 25543 (51.8) | 1976 (46.1) | 1236 (50.9) | 578 (46.4) |
| Primiparous | 15170 (26.5) | 13127 (26.6) | 1146 (26.7) | 600 (24.7) | 297 (23.9) |
| Multiparous | 10198 (17.8) | 8459 (17.2) | 969 (22.6) | 464 (19.1) | 306 (24.6) |
| Missing | 2553 (4.5) | 2166 (4.4) | 197 (4.6) | 126 (5.2) | 64 (5.1) |
| Neighborhood Deprivation Index, n (%)1 | |||||
| < −1 | 8178 (14.3) | 7157 (14.5) | 510 (11.9) | 361 (14.9) | 150 (12.0) |
| −1 to < 0 | 26738 (46.7) | 23173 (47.0) | 1920 (44.8) | 1093 (45.1) | 552 (44.3) |
| 0 to < 1 | 15518 (27.1) | 13231 (26.8) | 1275 (29.7) | 650 (26.8) | 362 (29.1) |
| ≥ 1 | 6711 (11.7) | 5640 (11.4) | 572 (13.3) | 320 (13.2) | 179 (14.4) |
| Missing | 109 (0.2) | 94 (0.2) | 11 (0.3) | 2 (0.1) | 2 (0.2) |
| Patient insurance status, n (%) | |||||
| Commercial | 49573 (86.6) | 42741 (86.7) | 3684 (85.9) | 2099 (86.5) | 1049 (84.3) |
| Medicare/Medicaid | 6328 (11.1) | 5401 (11.0) | 492 (11.5) | 272 (11.2) | 163 (13.1) |
| Other | 1353 (2.4) | 1153 (2.3) | 112 (2.6) | 55 (2.3) | 33 (2.7) |
| Current smoking, n (%) | |||||
| Yes | 1671 (2.9) | 1446 (2.9) | 115 (2.7) | 72 (3.0) | 38 (3.1) |
| No | 52026 (90.9) | 44874 (91.0) | 3892 (90.8) | 2154 (88.8) | 1106 (88.8) |
| Missing | 3557 (6.2) | 2975 (6.0) | 281 (6.6) | 200 (8.2) | 101 (8.1) |
| Cesarean delivery, n (%) | 18767 (32.8) | 14669 (29.8) | 2059 (48.0) | 1237 (51.0) | 802 (64.4) |
| COPS2 score at admission, mean (SD) | 10.10 (3.39) | 10.06 (3.16) | 10.30 (4.34) | 10.28 (4.43) | 10.53 (5.50) |
| Preterm delivery, n (%) | 7308 (12.8) | 4248 (8.6) | 1351 (31.5) | 917 (37.8) | 792 (63.6) |