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. 2024 Jul 24;14:17049. doi: 10.1038/s41598-024-61304-y

Table 4.

Association between atrial cardiopathy and stroke severity.

Moderate-to-severe stroke Severe stroke Continuous NIHSS
OR (95% CI) p OR (95% CI) p Beta p
Univariate 2.31 (1.68–3.17) < 0.001 5.58 (3.04–10.26) 0.001 0.292 < 0.001
Model 1 2.33 (1.67–3.26) < 0.001 5.40 (2.88–10.11) 0.001 0.287 < 0.001
Model 2 2.16 (1.46–3.20) < 0.001 4.89 (2.45–9.76) < 0.001 0.280 < 0.001
Sensitivity analyses
 Univariate 2.07 (1.35–3.17) 0.001 5.15 (2.45–10.83) < 0.001 0.259 < 0.001
 Model 1 2.37 (1.51–3.73) < 0.001 5.07 (2.34–11.02) < 0.001 0.274 < 0.001
 Model 2 2.23 (1.40–3.55) < 0.001 4.76 (2.13–10.61) < 0.001 0.266 < 0.001

Model 1: Age and sex adjusted;

Model 2: Adjusted for variables with a p < 0.1 in the univariate analysis for outcomes; (age, sex, dyslipidemia, atrial fibrillation, coronary artery disease, wake-up stroke, TOAST, FBG, triglyceride, total cholesterol, LDL).

Sensitivity analysis: excluding patients with atrial fibrillation or coronary artery disease. Two models were used:

Model 1: Age and sex adjusted;

Model 2: Adjusted for age, sex, dyslipidemia, wake-up stroke, TOAST, FBG, triglyceride, total cholesterol, LDL.

NIHSS National Institutes of Health Stroke Scale, OR odds ratio, CI confidence interval, TOAST Trial of Org 10172 in Acute Stroke Treatment, FBG fasting blood glucose, LDL low-density lipoprotein.