Figure 5.

Regulation of the rates of AAs and lipids by the increasing rate of insulin

(A) Temporal patterns of insulin with different increasing rates as input. The colors of the lines indicate different rates.

(B) The definition of RI in the time series for insulin and metabolites.

(C) Temporal pattern of metabolites as outputs. The colors of lines correspond to the colors of the inputs (B).

(D) The RI of the indicated metabolite against the rate of insulin in the simulation. The x axis of shows the duration of insulin, which is inversely proportional to the rate of insulin increase.

(E) Dynamic range of RI of metabolites. The color of the bar indicates the metabolic group (blue: AAs, green: lipids).