Table 2.

Baseline characteristics of individuals recruited for comparative proteomics analysis.

		All	AVB with COVID-19	COVID-19 without AVB	p value
Overall		19	9	10
Demographics
	Age, years, mean $\pm$ SD	51.0 $\pm$ 16.7	55.7 $\pm$ 18.3	46.8 $\pm$ 14.8	0.26
	Female sex, n (%)	9 (47.4)	3 (33.3)	6 (60.0)	0.37
	BMI, kg/$m^2$, mean $\pm$ SD	25.6 $\pm$ 3.8	25.1 $\pm$ 3.6	26.1 $\pm$ 4.1	0.58
	Hypertension, n (%)	7 (36.8)	5 (55.6)	2 (20.0)
	Diabetes, n (%)	3 (15.8)	3 (33.3)	0 (0.0)	0.09
	Coronary artery disease, n (%)	1 (5.3)	1 (11.1)	0 (0.0)	0.47
	Current or previous smoker, n (%)	5 (26.3)	3 (33.3)	2 (20.0)	0.63
	Current or previous cancer, n (%)	3 (15.8)	2 (22.2)	1 (10.0)	0.58
	Autoimmune disorder, n (%)	1 (5.3)	1 (11.1)	0 (0.0)	0.47
ECG on admission
	Third-Degree AVB, n (%)	9 (47.4)	9 (100.0)	-
	Permanent AVB, n (%)	6 (31.6)	6 (66.7)	-
Laboratory tests on admission
	WBC, ×${\mathrm{10}}^9$/L, median (Q1–Q3)	6.3 (5.3–7.4)	7.4 (5.2–9.4)	6.1 (5.0–7.0)	0.18
Lymphocyte count, ×${\mathrm{10}}^9$/L, median (Q1–Q3)		1.5 (1.2–2.2)	1.4 (0.9–2.1)	1.5 (1.3–2.4)	0.56
	hs-cTnI, ng/mL, median (Q1–Q3)	0.002 (0.002–0.009)	0.005 (0.002–0.027)	0.002 (0.002–0.005)	0.12
	NT-pro BNP, pg/mL, median (Q1–Q3)	96.1 (18.2–256.0)	206.0 (116.0–1098.0)	36.2 (16.9–75.3)	0.01*
	MYO, ng/mL, median (Q1–Q3)	33.8 (23.6–49.8)	48.5 (22.7–92.2)	27.6 (23.1–41.2)	0.21
	CK-MB, U/L, median (Q1–Q3)	0.8 (0.5–1.3)	1.3 (0.5–2.9)	0.7 (0.5–1.0)	0.13
	CRP, mg/L, median (Q1–Q3)	3.7 (2.1–5.7)	5.7 (4.7–9.7)	2.1 (1.5–2.3)	0.01*
	Creatinine, mg/dL, median (Q1–Q3)	65.2 (56.6–79.4)	66.1 (62.0–114.1)	58.2 (50.8–74.5)	0.06
	D-dimer, µg/mL, median (Q1–Q3)	0.4 (0.2–3.2)	2.9 (0.7–4.8)	0.2 (0.2–0.5)	0.03*
	ALT, IU/L, median (Q1–Q3)	25.0 (14.0–40.0)	26.0 (13.0–36.5)	21.5 (14.8–53.8)	0.82
	Albumin, g/L, median (Q1–Q3)	45.3 (40.1–46.5)	43.6 (35.4–45.6)	45.9 (45.2–48.1)	0.02*
Echocardiography on admission
	LVEDD, mm, mean $\pm$ SD	47.6 $\pm$ 4.2	50.3 $\pm$ 2.7	45.2 $\pm$ 3.8	0.01*
	LVEF, %, mean $\pm$ SD	64.3 $\pm$ 4.9	61.3 $\pm$ 4.4	63.0 $\pm$ 3.7	0.01*

AVB, atrioventricular block; BMI, body mass index; WBC, white blood cell; hs-cTnI, high-sensitivity cardiac troponin I; NT-pro BNP, N-terminal pro b-type natriuretic peptide; MYO, myoglobulin; CK-MB, creatine kinase; CRP, C-reactive protein; ALT, alanine transaminase; LVEDD, left ventricular end diastolic diameter; LVEF, left ventricular ejection fraction; SD, standard deviation; ECG, electrocardiogram. * indicates statistically significant; COVID-19, coronavirus disease 2019.