Figure 2. Cumulative Incidence Curves of Mortality, Disability, and Dementia for Social Isolation Change Groups, Stratified by Baseline Social Isolation Status.

Disability was measured as an activities of daily living score greater than 0, and dementia was defined as Alzheimer disease or Alzheimer disease–related dementia. The cumulative incidences for cardiovascular disease and stroke are listed in eFigure 3 in Supplement 1. SII indicates Social Isolation Index.