TABLE 2.
Summary of binding and PE2 cleavage phenotypes
| Virus | Heparin bindinga | Cell binding (% cpm bound) | PE2 content of virus particle (%) | Cleavage site | Substitution mutation |
|---|---|---|---|---|---|
| TR339 | − | 0.4 | 2.3 | Intact | |
| 39R1 | + | 7.6 | 14 | Intact | E2 Arg 1 |
| FDK70 | + | 1.0 | >90 | BXBB deleted | E2 Lys 70 |
| 39K70 | + | 34 | 1.5 | Intact | E2 Lys 70 |
| FDN1 | − | 1.8 | >90 | BXBB deleted | E2 Asn 1 |
| FD2 | − | 0.8 | >90 | −2, −1 deleted | |
| FD1 | + | 2.8 | >90 | −1 deleted | |
| FD | − | 0.2 | >90 | BXBB deleted | |
| 39N1 | + | 39 | >90 | Intact | E2 Asn 1 |
| 39V1 | + | 44 | 76 | Intact | E2 Val 1 |
| 39L1 | + | 39 | 69 | Intact | E2 Leu 1 |
a
+, present; −, absent.