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. Author manuscript; available in PMC: 2025 Jan 1.
Published in final edited form as: Placenta. 2023 Dec 15;145:117–125. doi: 10.1016/j.placenta.2023.12.016

Figure 4. Heatmap of significantly enriched pathways for K-562 cells treated with BeWo conditioned media, compared with unconditioned medium controls.

Figure 4.

After 24-hour incubation with conditioned media, RNA was isolated from K-562 cells and used for RNA sequencing, followed by differential gene and pathway enrichment analysis. Pathways significantly enriched with upregulated genes (FDR < 0.05, enrichment odds ratio > 1.1) are shown in red and pathways enrich with downregulated genes are shown in blue (FDR < 0.05, enrichment odds ratio < 0.9). Pathway categories of particular relevance to stem cell biology are shown in bold.