TABLE 1.
Primate | First injection
|
Time of MRI | Death
|
Survival (mo) | ||
---|---|---|---|---|---|---|
Virus | PFU | Time | Cause | |||
Group 1 | ||||||
T1122 | G207 | 107 | 3 mo | Sacrifice | ||
T9205 | G207 | 107 | Preop | 6 mo | Sacrifice | |
1 mo | ||||||
6 mo | ||||||
T9307 | G207 | 107 | 12 mo | Sacrifice | ||
T344 | G207 | 107 | 41 | |||
T317 | G207 | 107 | 41 | |||
T323 | G207 | 107 | 34 | |||
T432 | G207 | 107 | 7 mo | Inguinal hematoma | ||
T910805 | G207 | 107 | 4 mo | Pancreatitis | ||
T894 | G207 | 107 | Preop | 25 days | Fasting | |
10 days | ||||||
Group 2 | ||||||
T558 | G207 | 109 | 6 mo | 20 mo | Sacrifice | |
T413 | G207 | 109 | 7 mo | Aortic aneurysm | ||
Group 3 | ||||||
T348 | G207 | 107 | 11 mo | 41 | ||
25 mo | ||||||
T442 | G207 | 107 | 12 mo | 41 | ||
15 mo | ||||||
Group 4 | ||||||
T1057 | F | 103 | 5 days | Encephalitis | ||
T421 | Mock | 42 | ||||
T357 | Mock | 30 mo | Acute heart failure |
Primates were inoculated with G207 (107 PFU in 10 μl or 109 PFU in 180 μl), strain F, or virus buffer (Mock). Group 3 animals were reinoculated with G207 12 months after the initial inoculation. Preop, preoperatively.