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. 2024 Jul 19;14:16687. doi: 10.1038/s41598-024-67045-2

Table 5.

Intraoperative and postoperative characteristics of patients undergoing third molar extraction in the two groups.

Parameters Overall (n = 1260) General anesthesia (n = 1043) Intravenous sedation (n = 217) P-value
Intraoperative statistics
 Duration of surgery (min) 58.55 ± 31.85 60.36 ± 33.07 49.82 ± 23.33  < 0.001
 Duration of anesthesia (min) 87.66 ± 33.43 91.16 ± 33.97 70.85 ± 24.57  < 0.001
 Total fluid volume (ml) 270.56 ± 155.25 286.63 ± 160.89 193.32 ± 91.48  < 0.001
 Total blood loss (ml) 46.88 ± 62.50 51.56 ± 66.03 24.38 ± 33.40  < 0.001
BP
 Systolic BP (mmHg) 109.1 ± 13.49 107.6 ± 12.96 116.28 ± 13.72  < 0.001
 Diastolic BP (mmHg) 57.23 ± 9.52 56.42 ± 9.34 61.13 ± 9.44  < 0.001
 Mean BP (mmHg) 78.55 ± 9.80 77.63 ± 9.53 82.96 ± 9.89  < 0.001
 Episodes of hypotension 243 (19.29%) 225 (21.57%) 18 (8.29%)  < 0.001
 Ephedrine 13 (1.03%) 13 (1.25%) 0 (0%) 0.098
 Episodes of hypertension 24 (1.90%) 15 (1.44%) 9 (4.15%) 0.008
HR
 HR (beats/min) 79.54 ± 12.91 80.61 ± 12.97 74.39 ± 11.28  < 0.001
 Episodes of bradycardia 261 (20.71%) 189 (18.12%) 72 (33.18%)  < 0.001
 Atropine or glycopyrrolate 8 (0.63%) 6 (0.58%) 2 (0.92%) 0.559
 Episodes of tachycardia 98 (7.78%) 97 (9.30%) 1 (0.46%)  < 0.001
 Esmolol 5 (0.4%) 5 (0.48%) 0 (0%) 0.307
Saturation
 Saturation (%) 98.79 ± 0.89 98.70 ± 0.89 99.20 ± 0.76  < 0.001
 Saturation < 95% 12 (0.95%) 10 (0.96%) 2 (0.92%) 0.959
 Saturation < 90% 0 (0%) 0 (0%) 0 (0%)
Medication during recovery
 Opioid 202 (16.03%) 199 (19.08%) 3 (1.38%)  < 0.001
 NSAIDs 79 (6.27%) 78 (7.48%) 1 (0.46%)  < 0.001
 Antiemetics 7 (0.56%) 7 (0.67%) 0 (0%) 0.226
 Vasopressor 20 (1.59%) 0 (0%) 20 (9.22%)  < 0.001
 Anti-hypertensive 4 (0.32%) 4 (0.38%) 0 (0%) 0.361

Data are presented as numbers (%) or means ± standard deviations.

Episode of hypotension, systolic BP < 80% baseline; episodes of hypertension, systolic BP > 120% baseline; episodes of bradycardia, HR < 60/min; episodes of tachycardia, HR > 120/min.

BP blood pressure, HR heart rate, NSAIDs non-steroidal anti-inflammatory drugs.

Independent t-test was performed for continuous variables, and Fisher's exact test was performed for categorical variables.