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Multivariable Mendelian randomization analysis of causal effects of risk factors on esophageal disease after adjusting for birth weight. aP < 0.05. Helicobacter pylori phenotypes do not acquire sufficient single nucleotide polymorphisms in multivariable Mendelian randomization. GERD: Gastroesophageal reflux disease; BE: Barrett’s esophagus; EA: Esophageal adenocarcinoma; OR: Odds ratio; CI: Confidence interval; nSNPs: Number of single nucleotide polymorphisms.
