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Study schema. Sixty-three volunteers from the Cardiovascular Health Study (CHS) Cognition Study (CHS-CS) were used for this study. All of the volunteers received two sets of structural and perfusion MRIs during 2002-2009. The 63 included 40 volunteers from the University of Pittsburgh cohort of the CHS who also received neuropsychological assessment and structural MRIs during 1997-1999. None of the volunteers had AD when they were recruited for the CHS-CS.
