Figure 3.

Potential regulatory mechanisms of m⁶A modification in vascular aging. The aberrant m⁶A modification participates in various molecular and cellular mechanisms that lead to vascular aging, including oxidative stress, chronic inflammation, mitochondrial dysfunction, autophagy, DNA damage, and cellular senescence. This figure was created with the aid of Biorender (https://biorender.com/). ROS: reactive oxygen species; SG: stress granule; EC: endothelial cell; VSMC: vascular smooth muscle cell.