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Effects of a single intravenous (IV) injection of vehicle control (n = 6 eyes and n = 5 eyes, respectively) or (A) RG7774 0.003 mg/kg (n = 4 eyes), 0.3 mg/kg (n = 5 eyes) or 3.0 mg/kg in mice (n = 6 eyes) with lipopolysaccharide (LPS)-induced endotoxin-induced uveitis (EIU) and (B) RG7774 1.0 mg/kg (n = 4 eyes) in rats with LPS-induced EIU. * <0.05; **p < 0.01; ***p < 0.001 based on 1-way ANOVA, followed by Newman–Keuls post hoc analysis.
