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Owner-reported tolerance of the investigational product. No significant changes in (A) appetite, (B) vomiting, (C) diarrhea, (D) sleep quality, and (E) play quality were reported in either intervention or placebo phases of the study. (F) A moderate increase in the overall wellbeing score was observed in the intervention cohort. Results were expressed as means ± SD (n = 37). Data were analyzed by two-way ANOVA corrected for multiple comparisons with a Sidak test (*p < 0.05).
