Table 2.

Univariate (log rank) and Cox regression analyses

	Univariate analysis (log rank): p-value		Cox regression: HR (p-value)
	PFS	OS	PFS	OS
ECOG status (0–2 vs 3–4)	0.64	0.0068*	2.2 (0.18)	4.5 (0.002) *
CP score (A vs. B&C)	0.53	0.0078*	–	–
BCLC stage	0.00026*	0.012*	–	–
PVTT	0.00025*	0.002*	4.04 (0.02) *	3.5 (0.046) *
Tumor volume ≥ 37 cm3	0.032*	0.008*	2.62 (0.045) *	3.7 (0.012) *
AFP > 23 ng/ml	0.028*	0.54	1.9 (0.2)	1.2 (0.71)
TACE (postprogression)	0.13	0.88	–	–
Systemic therapy (postprogression)	0.00025*	0.65	–	–

CP Child–Pugh, PVTT portal vein tumor thrombus, AFP alpha-fetoprotein

*p-value < 0.05: statistically significant