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. 2024 May 8;39(9):2759–2772. doi: 10.1007/s00467-024-06389-3

Table 7.

Baseline correlates of dyslipidemia

High cholesterol (n = 630) High LDL cholesterol (n = 629) Low HDL cholesterol (n = 632) High triglycerides (n = 631)
OR [95%CI] p-value OR [95%CI] p-value OR [95%CI] p-value OR [95%CI] p-value
Age (yrs) 0.93 [0.88, 0.99] 0.0137 0.91 [0.84, 0.98] 0.0100 1.09 [1.03, 1.15] 0.0025 0.87 [0.82, 0.91]  < 0.0001
Sex (ref male) n.i n.i 0.43 [0.29, 0.65]  < 0.0001 n.i
Glomerular disease (ref CAKUT) 5.02 [2.65, 9.49]  < 0.0001 5.07 [2.47, 10.42]  < 0.0001 n.i 1.80 [0.90, 3.59] 0.0956
Other diagnosis (ref CAKUT) 1.43 [0.90, 2.26.] 0.1262 1.36 [0.76, 2.45] 0.3056 n.i 0.75 [0.49, 1.14] 0.1790
eGFR (ml/min/1.73 m2) 1.02 [1.00, 1.04] 0.0595 n.i 0.97 [0.95, 0.99] 0.0007 0.98 [0.97, 0.99] 0.0293
Time since CKD2 (years) n.i n.i 0.92 [0.88, 0.96] 0.0002 0.94 [0.91, 0.99] 0.0076
Log UACR 1.38 [1.22 1.57]  < 0.0001 1.22 [1.04, 1.43] 0.0159 0.84 [0.74, 0.94] 0.0032 n.i
Log hsCRP 0.85[0.74, 0.96] 0.0109 n.i 1.24[1.11, 1.39] 0.0002 n.i
BMI-SDS 1.26 [1.07, 1.48] 0.0057 1.21 [0.99, 1.49] 0.0577 n.i 1.20 [1.05, 1.37] 0.0090
Serum albumin n.i 0.95 [0.91, 0.99] 0.0274 0.93 [0.89, 0.96] 0.0001 0.95 [0.92, 0.99] 0.0078
Diastolic BP -SDS n.i n.i n.i 1.25 [1.06, 1.48] 0.0069
Lack of physical activity (ref ≥ 1 h per week) n.i 1.84 [1.00, 3.36] 0.0487 n.i 1.44 [0.95, 2.18] 0.0825
Serum bicarbonate 1.05 [1.00, 1.11] 0.0702 n.i 0.94 [0.89, 0.99] 0.0172 n.i
Serum hemoglobin n.i n.i n.i n.i
Non-fasting status (ref fasting) 1.19 [0.80, 1.78] 0.3884 1.28 [0.79, 2.07] 0.3223 0.94 [0.65, 1.37] 0.7611 0.90 [0.64, 1.28] 0.5555

Multivariable logistic regression for lipids (binary). Variables remaining significant at the 0.1 level after backward selection included, fasting status forced in the model

n.i. not included, OR odds ratio, CI confidence interval, ref reference category, UACR urinary albumin/creatinine ratio