Table 3.
Advantages and disadvantages of different cardiac imaging modalities in the diagnosis of cardiac involvement of acromegaly.
| Cardiac imaging modality | Advantages | Disadvantages |
| GLS/2DSTE | Available everywhere | Needs good image |
| Low-cost | Does not detect myocardial fibrosis | |
| 3DSTE | Offers additional parameters | Low feasibility in everyday practice |
| Eliminates directional limits of 2D speckle tracking | Accuracy highly depends on technical skills of operator | |
| Time-saving | Not yet readily available in developing countries | |
| Cardiac MRI | Higher spatial resolution | Expensive |
| Gold standard for the assessment of myocardial mass | Not readily available in developing countries | |
| Can precisely detect myocardial fibrosis | Cannot be used to patients with metal implanted on their bodies | |
| Can precisely assess RV systolic function |