Table 2. Characteristics of Infants in the Norwegian Neonatal Network.
| Characteristic | Infants, No. (%) (N = 1844) | P value | |
|---|---|---|---|
| Treatment-warranted ROP (n = 140) | ROP stages < treatment thresholds (n = 1704) | ||
| Gestational age, mean (SD), wk | 24.95 (1.57) | 26.46 (1.44) | <.001 |
| Birth weight, mean (SD), g | 695 (195) | 919 (235) | <.001 |
| Sex | |||
| Female | 57 (40.7) | 809 (47.5) | .13 |
| Male | 83 (59.3) | 895 (52.5) | |
| SGA status | 42 (30.0) | 384 (22.5) | .05 |
| Antenatal steroid use | 134 (95.7) | 1514 (88.8) | .007 |
| Apgar score at 5 min, median (IQR) | 7 (5-8) | 7 (6-9) | <.001 |
| Days on mechanical ventilation or CPAP, median (IQR) | 83 (67-103) | 51 (38-70) | <.001 |
| Days on supplemental oxygen, median (IQR) | 97 (77-131) | 59 (43-83) | <.001 |
| Days until full enteral feeds, median (IQR) | 13 (10-23) | 10 (7-13) | <.001 |
| Neonatal sepsis | 45 (32.1) | 307 (18.0) | <.001 |
| Sepsis episodes | |||
| 1 | 29 (20.7) | 264 (15.5) | .12 |
| 2 | 13 (9.3) | 36 (2.1) | <.001 |
| 3 | 3 (2.1) | 7 (0.4) | .04 |
| IVH grade 3-4 | 12 (8.6) | 92 (5.4) | .13 |
| cPVL | 7 (5.0) | 77 (4.5) | .83 |
| NEC requiring surgery | 20 (14.3) | 38 (2.2) | <.001 |
Abbreviations: CPAP, continuous positive airway pressure; cPVL, cystic periventricular leukomalacia; IVH, intraventricular hemorrhage; NEC, necrotizing enterocolitis; ROP, retinopathy of prematurity; SGA, small for gestational age.