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. 2024 Jul 5;11(7):687. doi: 10.3390/bioengineering11070687

Figure 4.

Figure 4

RT-PCR analysis of gingival fibroblasts incubated with HSC2 and TR146 necrotic cell lysates overnight in SB431542. RT-PCR analysis of gingival fibroblasts incubated with necrotic cell lysates with and without the TGF-β RI kinase inhibitor SB431542. Expression analysis showed that blocking TGF-β signalling reduced necrotic cell lysate-induced STC1, AREG, and C11orf96 expression in gingival fibroblasts. Data points represent four independent experiments. Data were normalized to untreated control, giving as x-fold changes. The analysis was based on a ratio-paired t-test.