Figure 12.

HIF-1α regulates the dynamic expression of Bax/Bcl-2 in yak oocytes and preimplantation parthenogenetic embryos through autophagy. (A,C,E,G,I,K) Immunofluorescence labeling of Bax and Bcl-2 proteins in oocytes, 2 cells, 4 cells, 8 cells, morula, and blastocysts of different treatment groups. (B,D,F,H,J,L) The relative expression levels of Bax and Bcl-2 proteins in oocytes, 2 cells, 4 cells, 8 cells, morula, and blastocysts of different treatment groups. Bar = 50 μm. The difference of different letters in the histogram was statistically significant (p < 0.05).