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. 2024 Jul 22;13(7):679. doi: 10.3390/antibiotics13070679

Table 1.

Summary of antibiotic resistance genes found and associated resistance mechanisms.

Family Gen Antibiotic
Family
Drug
Example
Resistance Mechanism
Example
Literature
References
bla Beta-lactams Imipenem Antibiotic Inactivation [24]
cat Phenicols Chloramphenicol Antibiotic Inactivation [29]
cfx Cefamycins Cefoxitin Antibiotic Inactivation [31]
dfr Diaminopyridines Trimethoprim Target modification [26]
erm Macrolides Erythromycin Target modification [32]
inu Lincosamides Clindamicin Antibiotic Inactivation [33]
mef Macrolides Erythromycin Efflux Pump [34]
msr Macrolides Erythromycin Efflux Pump [35]
oqx Multi-Drug Multi-Drug Efflux Pump [36]
tet Tetracyclines Doxicycline Efflux Pump, Target Modification, Antibiotic Inactivation [23]
vat Streptogramins Virginiamycin Antibiotic Inactivation [37]