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Dietary prebiotics reshape the gut microbiome and restore metabolic diseases. Abbreviations: TGR5: thiol guanosine receptor-5, GPR: G protein-coupled receptor, LPS: lipopolysaccharide, SCFA: short-chain fatty acid, Hs-CRP: high sensitivity C-reactive protein; ROS: reactive oxygen species; Akt: protein kinase B; p38; mitogen-activated protein kinases; ERK: extracellular signal-regulated kinase 1. → indicates induction and ⸺⸦ indicates suppression.
