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Ang2, podoplanin, and CLEC-2 staining intensity (expressed as optical density (OD)) in HCC patients treated with TKIs stratified according to sex.
| Protein | Females (n = 5) | Males (n = 18) | p |
|---|---|---|---|
| Ang2 | |||
| Endothelial | 0.623 ± 0.09 | 0.514 ± 0.07 | 0.008 |
| Hepatocyte (T) | 0.527 ± 0.15 | 0.468 ± 0.10 | 0.316 |
| Podoplanin | |||
| Endothelial | 0.800 ± 0.07 | 0.680 ± 0.11 | 0.036 |
| CLEC-2 | |||
| Hepatocyte (T) | 0.508 ± 0.06 | 0.597 ± 0.14 | 0.204 |
(Ang2, angiopoietin-2; T, tumor; CLEC-2, C-type lectin receptor).
