| Local | Uncommon or rare systemic causes |
| • Impacted teeth | • Down's syndrome |
| Iatrogenic | • Cleidocranial dysplasia |
| • Cytotoxic therapy | • Congenital hypopituitarism |
| • Radiotherapy | • Congenital hypothyroidism |
| • Gaucher's disease | |
| • Osteopetrosis | |
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