FIG. 1.

Lung eosinophilia and cytokine production in BALB/c mice. (A) Mice were primed with recombinant vaccinia virus expressing RSV G glycoprotein (VG) or control vaccinia virus (VSC11). Three weeks after priming, the mice were infected with RSV, and their lungs were harvested 5 days postchallenge. Sections of lung were stained for eosinophils, and the eosinophils present around blood vessels were enumerated. Each data point represents an average of eosinophils per millimeter of blood vessel length in an individual animal. (B) Mononuclear cells isolated from these lungs were stimulated with RSV in vitro, and the cytokines in the supernatants were analyzed by ELISA. Each data point represents an individual mouse. ∗, P < 0.05 (compared to VSC11-primed mice) by Student’s t test.