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. 2024 Jul 19;13(7):864. doi: 10.3390/antiox13070864

Figure 1.

Figure 1

Effect of DOX and CD on the cell viability of A375 human melanoma cells, H9C2 rat cardiac myoblasts and normal human dermal fibroblasts (NHDF). (A–F): A375 (A,B), H9C2 (C,D) and NHDF (E,F) were treated with increasing concentrations of DOX (A,C,E) and CD (B,D,F) for 24, 48, 72 and 96 h. (G) For comparing A375, H9C2 and NHDF, cells were treated with different concentrations of DOX alone or in combination with CD for 96 h. Cell viability was determined via the MTT assay and mock-treated control (ct) was set to 100%. Data represent means ± SEM, n ≥ 3. (G) One-way ANOVA was used to determine statistical significance in A375 cells compared to control (white bar). Two-way ANOVA was used in H9C2 and NHDF to compare CD-untreated (0 µM) with CD-treated cells (5 µM). ** p ≤ 0.01, *** p ≤ 0.001.