AKT	Protein kinase B	LUSC	Lung squamous cell carcinoma
ALK	Anaplastic lymphoma kinase	MAPK	Mitogen-activated protein kinase
AMPK	AMP-activated protein kinase	MDM2	Mouse double minute 2 homolog
AT1	Alveolar type 1	MDMX	Mouse double minute X
AT2	Alveolar type 2	mRNA	Messenger RNA
ATM	Ataxia telangiectasia mutated	mTOR	Mammalian target of rapamycin
ATR	Ataxia telangiectasia and Rad3-related protein	NGS	Next-generation sequencing
CDKN2A	Cyclin-dependent kinase inhibitor 2A	NSCLC	Non-small-cell lung cancer
CTD	C-terminal domain	OD	Oligomerization domain
ctDNA	Circulating tumor DNA	p53RE	p53-response elements
DBD	DNA-binding domain	PARP	Poly-ADP ribose polymerase
DLL3	Delta-like ligand 3	PD-1	Programmed cell death protein 1
DNA	Deoxyribonucleic acid	PD-L1	Programmed cell death 1 ligand 1
DNMT	DNA methyltransferase	PI3K	Phosphatidylinositol 3-kinase
EGFR	Epidermal growth factor receptor	PRD	Proline-rich domain
FLp53	Full-length p53	PTEN	Phosphatase and tensin homolog
GOF	Gain of function	Rap1A	Ras-associated protein 1A
HDAC	Histone deacetylase	Rb1	Retinoblastoma 1 protein
ICIs	Immune checkpoint inhibitors	RhoC	Ras homolog family member C
JNK	c-Jun N-terminal kinase	SCLC	Small-cell lung cancer
LC	Lung cancer	TAD	Transactivation domain
LOF	Loss of function	YAP	Yes-associated protein
LUAD	Lung adenocarcinoma