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. 2024 Jul 11;13(14):1184. doi: 10.3390/cells13141184

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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FSO affects the expression of components of glutamatergic transmission 21 days post TMT intoxication. Relative protein abundances of GluN1 (a), GluN2A (c), GLT-1 (d), GluN2b (e), and PSD-95 (f) in the crude hippocampal membrane fractions of control (Ctrl), flaxseed oil (FSO)-treated, trimethyltin (TMT)-treated, and flaxseed oil-treated TMT-intoxicated (FSO+TMT) animals assessed by Western blot analysis. Bars represent mean protein abundance relative to β-actin ± SD, from n = 5 hippocampi per group. (b) Representative immunoblots of investigated proteins of Ctrl, FSO, TMT, and FSO+TMT animals. β-actin was probed to ensure equal protein loading. Significance shown inside the graphs: * p < 0.05 or less relative to Ctrl; # p < 0.05 or less relative to TMT.