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. 2024 Jun 26;12(7):1417. doi: 10.3390/biomedicines12071417

Table 1.

The table shows the most known surrogate indices of insulin resistance.

Indices Metabolic
State
Formula Cutoff
Values
References
HOMA-IR Fasting I mU/mL × G mg/dL/405 >4.65 [11]
TyG Fasting Ln [TG mg/dL × G mg/dL/2] >9.36 [12]
TG/HDLc Fasting TG mg/dL/HDLc mg/dL >2.75 for men
and >1.65 for women
[13]
Insulin Fasting I mU/L >12.2 [14]
GIR Fasting G mmol/L/I mU/L <7 [15]
VAI Fasting Men: (waist cm/39.68 + [1.88 × BMI]) × (TG mmol/L/1.03) × (1.31/HDLc mmol/L);
Women: (waist cm/36.58 + [1.89 × BMI]) × (TG mmol/L/0.81) × (1.52/HDLc mmol/L);
>0.34 [16]

Abbreviations: HOMA: homeostasis model of assessment; I: insulin; G: glucose; GIR: glucose to insulin ratio; VAI: visceral adiposity index; TG: triglycerides; HDLc: high-density lipoprotein cholesterol; TG/HDLc: triglyceride to high-density lipoprotein cholesterol ratio; TyG: triglycerides × fasting glucose.