Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jun 27;12(7):1439. doi: 10.3390/biomedicines12071439

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The extent of apoptosis was measured in terms of caspase-3 activity after induction of apoptosis in transfected (Control-siRNA, Bax+Bak-siRNA) and untransfected (Cells only) HCECs: (a) Apoptosis was induced using Staurosporine (250 nM for 6 h) after 96 h transfection. (b) Apoptosis was induced using etoposide (42.5 µM for 21 h) after 96 h transfection. Note that in both cases, the apoptosis rate was significantly reduced due to the knockdown of pro-apoptotic proteins Bax and Bak. (microplate reader Fluoroskan Ascent FL; n = 3, mean ± s.e.m., Friedman-Test posthoc Dunn’s multiple comparison test: * p < 0.05).