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. 2024 Jun 26;14(7):763. doi: 10.3390/biom14070763

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Volcano plots representing differentially abundant proteins in PRGF supernatants (SPs) and Immunosafe-treated PRGF supernatants (INSPs) between healthy (H) and pathological donors: dermatitis (D), psoriasis (P) and lichen sclerosus (L). The plots were constructed using log2 fold-change (log2FC) and p values. The colored dots represent the following cases: proteins upregulated in PRGF samples from pathological donors (blue), not differentially abundant proteins (green), and proteins downregulated in PRGF samples from pathological donors (red), at p ≤ 0.05.