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. 2024 Jul 4;14(7):797. doi: 10.3390/biom14070797

Figure 14.

Figure 14

Peptidomimetic covalent SARS-CoV-2 Mpro inhibitor N3 and examples of its structurally closely related compounds (maximum common substructure (MCS)) with known Mpro inhibitory activity from the PubChem Database. The low potency criterion was IC50 or Ki > 10 μM or Inh% at 20 M < 75%.