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. 2024 Jul 12;18:1417856. doi: 10.3389/fnint.2024.1417856

Figure 3.

Figure 3

Information systems or psychoneuroimmunoendocrine axis. At the top within the human being, the psyche or consciousness harbors thoughts and emotions. The communication interface between the psyche and the physical body is carried out through the nervous system. The neuroimmune axis transmits chemical signals through cytokines and neurotransmitters. The neuroendocrine axis involves chemical transmitters, such as hormone-releasing factors and hormones. The immunoendocrine axis comprises chemical transmitters of hormones and cytokines. This dynamic adaptation of the unity of being takes place through feedback loops between the axes, adjusting to the internal circumstances of the human body and the external conditions of the ecosystem. Thus, the unity of being is configured, establishing a direct and continuous relationship with the environment. (Source: Own elaboration).