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. 2024 Jul 12;18:1417856. doi: 10.3389/fnint.2024.1417856

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Copyright © 2024 Bustamante, Pinilla Bonilla and Restrepo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sensitization processes: with nonlinear mechanisms following SARS-CoV-2 infection including: (A) sensitization-irritation of peripheral receptor through immunological synapse with immune cell or directly by the virus, (B) sensitization-irritation of the vagus nerve, (C) sensitization-irritation of the brainstem solitary tract nucleus and parabrachial regions, (D) sensitization-irritation of the limbic system, (E) sensitization-irritation of the cortex (Source: Own elaboration).