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. 2000 Feb 19;320(7233):495–498. doi: 10.1136/bmj.320.7233.495
  Study   Treatment NYHA class*   Outcome




MDC Metoprolol II, III Improved clinical state without effect on survival. Reduction in need for transplantation in patients with dilated cardiomyopathy
CIBIS I Bisoprolol II, III Trend (non-significant) towards improved survival
ANZ trial Carvedilol I, II Carvedilol superior to placebo for morbidity and mortality
Carvedilol (US) Carvedilol II, III Carvedilol superior to placebo for morbidity and mortality
CIBIS II Bisoprolol III, IV Bisoprolol superior to placebo for morbidity and mortality
MERIT-HF Metoprolol II, III Metoprolol superior to placebo for morbidity and mortality