Figure 1.

The link between inflammation and obesity. The illustration presents normal adipose tissue transformation into inflamed adipose tissue which produces cytokines (IL-6, IL-1β, TNFα) that recruit neutrophils into the adipose tissue. Prolonged inflammation led to increased cytokine production and monocytes recruitment in the inflamed adipose tissue, which will be translated into chronic inflammation in the adipocytes. The chronic inflammation creates a positive feedback loop that maintains the inflammatory status within the adipose tissue. The figure was created with Biorender.