Table 2-. Microtubule dynamics in yeast cells.

Values are median ± 95% confidence interval. N = number of microtubules analyzed. Values in boldface are significantly different from wild-type controls (p < 0.05).

genotype	wild-type	wild-type	β3lat	β3lat	A315T	A315T	β3tail	β3tail
2.5 μM EpothiloneA	−	+	−	+	−	+	−	+
N	20	19	18	18	15	21	15	14
Median Length (μm)	1.05 ± 0.03	1.30 ± 0.04	1.20 ± 0.06	1.15 ± 0.04	1.15 ± 0.05	1.63 ± 0.03	1.30 ± 0.07	1.36 ± 0.02
Coefficient of Variation	0.38 ± 0.06	0.16 ± 0.04	0.41 ± 0.02	0.27 ± 0.06	0.32 ± 0.05	0.09 ± 0.01	0.37 ± 0.04	0.12 ± 0.04
Polymerization Rate (μm/min)	1.38 + 0.20	---	1.75 + 0.41	---	1.14 + 0.42	---	1.21 + 0.19	---
Depolymerization Rate (μm/min)	1.69 ± 0.34	---	2.30 ± 0.48	---	1.74 ± 0.55	---	2.10 ± 0.50	---
Catastrophe Frequency (events/min)	0.39 ± 0.05	---	0.8 ± 0.17	---	0.31 ± 0.10	---	0.61 ± 0.30	---
Percent Paused	22 ± 13	---	26 ± 12	---	29 ± 17	---	21 ± 14	---