Table 3. Microtubule dynamics in HeLa cells.
Values are median ± 95% confidence interval. N = number of growing microtubules analyzed. Values in boldface are significantly different from wild-type controls (p < 0.05).
| Overexpressed μ-tubulin | TUBB2b | TUBB3 | TUBB3:lat | TUBB3:I189V | TUBB3:T315A | TUBB3:V351T |
|---|---|---|---|---|---|---|
| N | 21395 | 21531 | 25524 | 26217 | 12881 | 21125 |
| Growth Speed (μm/min) | 9.1 ± 0.06 | 10.01 + 0.08 | 9.68 + 0.07 | 10.33 + 0.08 | 9.95 + 0.07 | 10.34 + 0.08 |
| Comet Duration (seconds) | 12 | 10 | 12 | 12 | 12 | 10 |
| Growth Events / μm2 / min | 0.30 ± 0.04 | 0.34 ± 0.04 | 0.36 ± 0.03 | 0.40 ± 0.03 | 0.29 ± 0.04 | 0.38 ± 0.03 |