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. 2024 Jul 20;15(7):952. doi: 10.3390/genes15070952

Figure 3.

Figure 3

Wild-type and SINE insertion nucleotide and amino acid sequences. The wild-type sequence commencing at the flanking sequence (highlighted in yellow) of the SINE to the end of exon 4 of FAM161A is shown in (A). The top row is the nucleotide sequence, the second row is the amino acid translation and the bottom row is the amino acid position in the protein. (B) The full SINE sequence (210 bp) confirmed by Sanger sequencing is shown with the flanking sequence highlighted in yellow. (C) The SINE, again with the flanking sequence highlighted in yellow, is shown with the amino acid translation on the second row and the protein position on the bottom row. The SINE remains in frame and terminates with a stop codon (marked with an asterix in red), extending exon 4 by 39 amino acids compared to the wild-type sequence.