Table 2.

Basic stage, symptoms, and principles of treatment of skin and tissue necrosis.

Stage	Symptom	Treatment
Impending Necrosis (Ischemic state)	Skin color-purple of reticular pattern Pain swelling	Decompression: Hyaluronidase, Puncture and drainage, Warm massage Revascularization: PGE1 (vasodilator) IV injection, Hyperbaric O2, Aspirin
Skin Necrosis (Infection and wound healing state)	Pustule Eschar	Infection control: Antibiotics, Removal of pustule Dressing: Antibiotics gauze Growth factor: EGF/PDRN/PRP/stem cell
Scar Formation (Skin defect)	Erythematous scar Depressed scars	Scar treatment: Vascular laser, Fractional laser, Skin graft