Table 6.

Impact of chlorogenic acids on the MAPK/NFκB pathway in colorectal cancer models.

Trend (↑ ↓)/Target	Study Model	Reference, Year
↑ NF-κB	HT-29—cell culture	[80], 2023
↓ AP-1 ↓ NFκB ↓ JNK ↓ ERK ↓ MAPK	HCT116—cell culture	[83], 2022
↓ NFκB ↓ Toll-like receptor 4 (TLR4)	LPS-induced SW480—cell culture	[90], 2023
↑ p-ERK	SW480—cell culture	[98], 2022
↑ p-ERK	HT-29—cell culture	[98], 2022
↓ NFκB	Sprague Dawley AOM-induced rats	[100], 2016
↓ ERK ↓ NFκB	HT-29—cell culture	[107], 2011

Note: ↑ = up-regulation; ↓ = down-regulation.