Table 1.

Characteristics of COPDGene and DHS participants of European ancestry included in the GWA analysis. Medical conditions are by patient self-report. For continuous variables, the mean is given first, followed by the standard deviation in parentheses.

	COPDGene	DHS
Sample size	6144	1115
Sex (% male)	52.4%	46.6%
Age (years)	62.0 (8.8)	62.3 (9.3)
BMI (kg/m2)	28.7 (6.0)	31.8 (6.5)
Diabetes mellitus (%)	12.1%	83.9%
High blood pressure (%)	42.2%	85.9%
High cholesterol (%)	45.0%	49.2%
Current smoking (%)	39.2%	17.0%
Former smoking (%)	60.8%	42.0%
Never smoking (%)	-	41.0%
CAC (mean [min–max])	202.1 [0–4970]	168.2 [0–5041.5]
CAC > 0 (%)	64.6%	92.5%