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. 2024 Jul 21;25(14):7958. doi: 10.3390/ijms25147958

Figure 1.

Figure 1

Gallic acid isolated from L. indica (GI) and gallic acid commercial standard (GA) inhibit cell proliferation and induce apoptosis in CML cell lines in a similar manner. (A,B) Drug response curve of K562 and LAMA84 cells to GI and GA. (C,D) GI and GA significantly induce apoptosis in CML cells. Treatment was 72 h. (E,F) Western immunoblotting of pro-apoptotic proteins shows an increase in both caspase 3 and PARP cleavage after 72 h of GI and GA treatment, respectively, in LAMA84 cells. β-actin serves as a loading control. Data are representative of at least three independent triplicates. * indicates p < 0.05 and ** indicates p < 0.01.