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Indicators of the potential mechanisms of the pro- and anti-cancer effects of ADSCs, as well as the possible impact of cancer cells on ADSCs, promoting their neoplastic transformation. Unspecified factors secreted by ADSCs cause apoptosis and the inhibition of cancer cell proliferation in co-cultures in vitro. On the other hand, cancer cells can, through an unknown mechanism, cause the malignant transformation of ADSCs, manifested by the expression of a cancerous phenotype.
